User blog comment:Blueyhale/Powers of the Pariah Gene/@comment-8881468-20151215103005

as per the cain novels ( his aide jurgen is a pariah) they cannot turn off the effect. and they do dampen demons or f.e. psychic effects from tyranids and they turn psykers pretty bonkers or uncomfortabvle and  even unable to move (see ther end of "Pandorax" where a GK GM is strapped with several  pariahs and thus pretty much unable to do anyhting.